Hi Paulie,
When you say setting up a business, I assume you don't mean organizing as an LLC or Incorporating, but simply mean operating as a business for tax purposes.
Here are some relevant IRS publications that you might find useful
Pub 334 Tax Guide for Small Business
Pub 463 Travel, Entertainment, Gift, and Car Expenses
Pub 535 Business Expenses
Pub 583 Starting a Business and Keeping Records
Pub 587 Business Use of Your Home
Pub 946 How to Depreciate Property
Pub 3995 Recognizing Illegal Tax Avoidance Schemes
Here is a useful link also.
https://www.irs.gov/Businesses/Small-Bu ... a-Business
As mentioned by Stan, the IRS has a new option for home office deductions which eliminates the requirement for "Depreciation Recapture" when you sell your home.
https://www.irs.gov/Businesses/Small-Bu ... -Deduction
Another good idea is to look at Schedule C and organize and total your expenses by the categories shown on that form and give your tax accountant totals. You can still point out any expense to your accountant that you included that you were not sure about. It is much preferred than to hand your tax accountant a "shoebox" full of receipts. You will get a better and less expensive tax return preparation.
As far as business expenses in general, keep this in mind from the IRS website:
What Can I Deduct?
To be deductible, a business expense must be both ordinary and necessary. An ordinary expense is one that is common and accepted in your trade or business. A necessary expense is one that is helpful and appropriate for your trade or business. An expense does not have to be indispensable to be considered necessary.
Here is one more good link.
http://www.thetaxadviser.com/issues/201 ... c2013.html
The main things I would encourage is
A) Develop an organized method to capture all your business expenses by major category - EG Separate business checking account and Credit Cards
B) Do not get overly aggressive in your deductions. "Pigs grow fat, and hogs get slaughtered"
You also have three other issues that are a factors or things to consider.
#1 Are you operating as a Hobby or Business? - If you are normally showing a profit, than this should not be an issue.
#2 Home office deductions - You must use the area exclusively and on a regular basis, either as your principal place of business or a setting to meet or deal with patients, clients or customers. “Exclusively” means the space is used just for work. You should be fine because most home studio serve only that single purpose.
#3 "Mixed use" / "Listed Property" - Listed property includes cars and other property used for transportation, property used for entertainment, and certain computers. - Your car would fall under this category, but your computer should be ok because I assume your computer is dedicated to your music business. Basically, such items are subject to special reporting and depreciation rules.
Best of luck to you!
fwiw I have been an Enrolled Agent since 2000